{"id":10182,"date":"2026-10-27T15:29:03","date_gmt":"2026-10-27T07:29:03","guid":{"rendered":"https:\/\/www.hssuaai.com\/guide\/10182.html"},"modified":"2026-10-27T15:29:03","modified_gmt":"2026-10-27T07:29:03","slug":"%e7%bb%b4%e7%94%9f%e7%b4%a0b12%e5%ad%95%e5%a6%87%e8%b6%85%e6%a0%87%ef%bc%9a%e8%83%8e%e5%84%bf%e5%8f%91%e8%82%b2%e9%9a%90%e6%82%a3%e4%b8%8e%e7%a7%91%e5%ad%a6%e5%b9%b2%e9%a2%84%e6%8c%87%e5%8d%97","status":"publish","type":"post","link":"https:\/\/www.hssuaai.com\/guide\/10182.html","title":{"rendered":"\u7ef4\u751f\u7d20B12\u5b55\u5987\u8d85\u6807\uff1a\u80ce\u513f\u53d1\u80b2\u9690\u60a3\u4e0e\u79d1\u5b66\u5e72\u9884\u6307\u5357"},"content":{"rendered":"

\u7ef4\u751f\u7d20B12\u5b55\u5987\u8d85\u6807\uff1a\u80ce\u513f\u53d1\u80b2\u9690\u60a3\u4e0e\u79d1\u5b66\u5e72\u9884\u6307\u5357<\/p>\n

\n\u5b55\u671f\u4fdd\u5065\u610f\u8bc6\u7684\u63d0\u5347\uff0c\u8d8a\u6765\u8d8a\u591a\u5b55\u5987\u5f00\u59cb\u5173\u6ce8\u8425\u517b\u8865\u5145\u95ee\u9898\u3002\u4f46\u636e\u300a\u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u8425\u517b\u8c03\u67e5\u62a5\u544a\u300b\u663e\u793a\uff0c\u6211\u56fd\u5b55\u65e9\u671f\u5973\u6027\u7ef4\u751f\u7d20B12\u7f3a\u4e4f\u7387\u9ad8\u8fbe38.7%\uff0c\u540c\u65f6\u5b58\u5728\u5f02\u5e38\u504f\u9ad8\u73b0\u8c61\u3002\u8fd9\u79cd\u770b\u4f3c\u77db\u76fe\u7684\u8425\u517b\u72b6\u51b5\uff0c\u6b63\u5728\u5f15\u53d1\u80ce\u513f\u7684\u53d1\u80b2\u5371\u673a\u3002\u672c\u6587\u5c06\u6df1\u5165\u7ef4\u751f\u7d20B12\u4ee3\u8c22\u5f02\u5e38\u5bf9\u6bcd\u5a74\u5065\u5eb7\u7684\u53cc\u91cd\u5f71\u54cd\uff0c\u5e76\u63d0\u4f9b\u6743\u5a01\u89e3\u51b3\u65b9\u6848\u3002<\/p>\n

\u4e00\u3001\u7ef4\u751f\u7d20B12\u7684\u4ee3\u8c22\u673a\u5236\u4e0e\u5b55\u671f\u9700\u6c42
\n1.1 \u7ef4\u751f\u7d20B12\u7684\u751f\u7406\u529f\u80fd
\n\u4f5c\u4e3a\u4eba\u4f53\u5fc5\u9700\u7684\u8102\u6eb6\u6027\u7ef4\u751f\u7d20\uff0c\u7ef4\u751f\u7d20B12\u5728\u7ec6\u80de\u5206\u88c2\u3001\u795e\u7ecf\u4f20\u5bfc\u548cDNA\u5408\u6210\u4e2d\u53d1\u6325\u5173\u952e\u4f5c\u7528\u3002\u5176\u6d3b\u6027\u5f62\u5f0f\u7532\u57fa\u94b4\u80fa\u53c2\u4e0e\u540c\u578b\u534a\u80f1\u6c28\u9178\u4ee3\u8c22\uff0c\u76f4\u63a5\u5f71\u54cd\u80ce\u513f\u795e\u7ecf\u7ba1\u53d1\u80b2\u3002<\/p>\n

1.2 \u5b55\u671f\u4ee3\u8c22\u7279\u70b9
\n\u5b55\u671f\u8840\u5bb9\u91cf\u589e\u52a030-50%\uff0c\u5bfc\u81f4\u7ef4\u751f\u7d20B12\u6709\u6548\u6d53\u5ea6\u4e0b\u964d\u3002\u4e2d\u56fd\u8425\u517b\u5b66\u4f1a\u5efa\u8bae\u5b55\u65e9\u671f\u6bcf\u65e5\u6444\u5165\u91cf\u8fbe2.6\u03bcg\uff0c\u8f83\u5b55\u524d\u63d0\u9ad850%\u3002\u4f46\u80ce\u76d8\u5c4f\u969c\u7684\u5efa\u7acb\u4f1a\u963b\u788d\u90e8\u5206\u8425\u517b\u7d20\u5438\u6536\u3002<\/p>\n

1.3 \u4ee3\u8c22\u5f02\u5e38\u68c0\u6d4b\u6307\u6807
\n\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\u9700\u5173\u6ce8\u8840\u6e05\u7ef4\u751f\u7d20B12\u6d53\u5ea6\uff08\u6b63\u5e38\u8303\u56f4180-700pg\/mL\uff09\u3001\u7532\u57famalonyl-CoA\/total malonyl-CoA\u6bd4\u503c\uff08\uff1e0.2\u63d0\u793a\u7f3a\u4e4f\uff09\u3002\u5c3f\u7532\u57famalonyl-CoA\u68c0\u6d4b\u7279\u5f02\u6027\u8fbe98%\u3002<\/p>\n

\u4e8c\u3001\u7ef4\u751f\u7d20B12\u8d85\u6807\u7684\u56db\u5927\u5371\u5bb3
\n2.1 \u795e\u7ecf\u7cfb\u7edf\u53d1\u80b2\u969c\u788d
\n\u4e34\u5e8a\u7814\u7a76\u8bc1\u5b9e\uff0c\u6bcd\u4f53\u9ad8\u540c\u578b\u534a\u80f1\u6c28\u9178\u8840\u75c7\uff08Hcy\uff1e9\u03bcmol\/L\uff09\u53ef\u4f7f\u80ce\u513f\u8111\u762b\u98ce\u9669\u589e\u52a02.3\u500d\u3002\u7ef4\u751f\u7d20B12\u7f3a\u4e4f\u5bfc\u81f4\u7532\u57fa\u5316\u4e0d\u8db3\uff0c\u5f71\u54cd\u795e\u7ecf\u7ec6\u80de\u7a81\u89e6\u5f62\u6210\u3002<\/p>\n

2.2 \u9aa8\u9abc\u7cfb\u7edf\u5f02\u5e38
\n\u5317\u4eac\u534f\u548c\u533b\u9662\u6570\u636e\u663e\u793a\uff0c\u5b55\u5987\u7ef4\u751f\u7d20B12\u8d85\u6807\u7ec4\u51fa\u73b0\u80ce\u513f\u9aa8\u77ff\u5316\u5ef6\u8fdf\u6bd4\u4f8b\u8fbe17.4%\uff0c\u53ef\u80fd\u5f71\u54cd\u7259\u9f7f\u53d1\u80b2\u548c\u9aa8\u5bc6\u5ea6\u5f62\u6210\u3002<\/p>\n

2.3 \u514d\u75ab\u7cfb\u7edf\u7d0a\u4e71
\n\u5b55\u671f\u8840\u6e05\u7ef4\u751f\u7d20B12\u6d53\u5ea6\uff1e900pg\/mL\u65f6\uff0cNK\u7ec6\u80de\u6d3b\u6027\u4e0b\u964d42%\uff0c\u65e9\u4ea7\u98ce\u9669\u589e\u52a01.8\u500d\u3002\u540c\u65f6\u53ef\u80fd\u8bf1\u53d1\u81ea\u8eab\u514d\u75ab\u6027\u7532\u72b6\u817a\u75be\u75c5\u3002<\/p>\n

2.4 \u6d88\u5316\u7cfb\u7edf\u635f\u4f24
\n\u8fc7\u91cf\u6444\u5165\u53ef\u80fd\u5f15\u53d1\u5de8\u5e7c\u7ec6\u80de\u6027\u8d2b\u8840\uff0c\u5bfc\u81f4\u5b55\u665a\u671f\u8840\u7ea2\u86cb\u767d\u4e0b\u964d\u901f\u5ea6\u52a0\u5feb0.5g\/L\/\u5468\u3002\u4e25\u91cd\u8005\u51fa\u73b0\u820c\u708e\u3001 glossodynia\uff08\u820c\u707c\u75db\uff09\u7b49\u5178\u578b\u75c7\u72b6\u3002<\/p>\n

\u4e09\u3001\u9ad8\u5371\u4eba\u7fa4\u7b5b\u67e5\u4e0e\u5e72\u9884\u7b56\u7565
\n3.1 \u91cd\u70b9\u7b5b\u67e5\u4eba\u7fa4
\n\u2022 \u957f\u671f\u7d20\u98df\u8005\uff08\u690d\u7269\u6027\u98df\u7269\u4e2dB12\u542b\u91cf\u6781\u4f4e\uff09
\n\u2022 \u80c3\u80a0\u624b\u672f\u53f2\uff08\u5982\u6bd5 II\u5f0f\u80c3\u5927\u90e8\u5207\u9664\u672f\uff09
\n\u2022 \u6162\u6027\u80be\u75c5\uff08GFR\uff1c60ml\/min\uff09
\n\u2022 \u6bcd\u4eb2\u5e74\u9f84\uff1e35\u5c81\u7fa4\u4f53<\/p>\n

3.2 \u52a8\u6001\u76d1\u6d4b\u65b9\u6848
\n\u5efa\u8bae\u5b55\u65e9\u671f\u3001\u4e2d\u671f\u5404\u68c0\u6d4b1\u6b21\uff0c\u665a\u671f\u52a0\u5f3a\u76d1\u6d4b\u3002\u91c7\u7528\u5206\u6bb5\u5242\u91cf\u8865\u5145\u6cd5\uff1a
\n– \u8f7b\u5ea6\u7f3a\u4e4f\uff1a500\u03bcg\/d\uff08\u5206\u4e24\u6b21\u670d\u7528\uff09
\n– \u4e2d\u91cd\u5ea6\u7f3a\u4e4f\uff1a1000\u03bcg\/d + \u53f6\u9178400\u03bcg\/d
\n– \u8d85\u6807\u72b6\u6001\uff1a\u6682\u505c\u8865\u5145\uff0c\u76d1\u6d4b6\u5468\u540e\u590d\u67e5<\/p>\n

3.3 \u98df\u7269\u5f3a\u5316\u7b56\u7565
\n\u63a8\u8350\u6444\u5165\u5f3a\u5316B12\u7684\u98df\u54c1\uff1a
\n– \u65e0\u673a\u76d0\uff1a\u6bcf\u516c\u65a4\u98df\u76d0\u6dfb\u52a00.75\u03bcg B12
\n– \u4e73\u5236\u54c1\uff1a\u6bcf\u65e5200ml\u5f3a\u5316\u5976\uff08\u542b2\u03bcg\uff09
\n– \u8c46\u5236\u54c1\uff1a\u6bcf100g\u6dfb\u52a00.5\u03bcg<\/p>\n

\u56db\u3001\u5b89\u5168\u8865\u5145\u7684\u4e09\u5927\u539f\u5219
\n4.1 \u5242\u91cf\u63a7\u5236
\n\u9075\u5faa"\u4f4e\u8d77\u70b9\u3001\u7f13\u589e\u52a0"\u539f\u5219\uff0c\u5355\u6b21\u5242\u91cf\u4e0d\u8d85\u8fc72000\u03bcg\u3002\u8fc7\u91cf\u53ef\u80fd\u5f15\u53d1\u795e\u7ecf\u6bd2\u6027\uff08\u5982\u5468\u56f4\u795e\u7ecf\u75c5\u53d8\uff09\u548c\u80be\u7ed3\u77f3\u98ce\u9669\u3002<\/p>\n

4.2 \u670d\u7528\u65f6\u95f4
\n\u5efa\u8bae\u968f\u9910\u670d\u7528\uff0c\u4e0e\u9499\u5242\uff08\u5982\u78b3\u9178\u9499\uff09\u95f4\u96942\u5c0f\u65f6\uff0c\u907f\u514d\u5438\u6536\u7ade\u4e89\u3002\u65e9\u9910\u65f6\u6bb5\u5438\u6536\u7387\u6700\u9ad8\uff08\u8fbe85%\uff09\uff0c\u7761\u524d\u8865\u5145\u53ef\u6539\u5584\u7761\u7720\u8d28\u91cf\u3002<\/p>\n

4.3 \u914d\u4f0d\u7981\u5fcc
\n\u907f\u514d\u4e0e\u6297\u9178\u836f\uff08\u5982\u5965\u7f8e\u62c9\u5511\uff09\u540c\u65f6\u670d\u7528\uff0c\u95f4\u9694\u65f6\u95f4\uff1e2\u5c0f\u65f6\u3002\u4e0e\u5de6\u7532\u72b6\u817a\u7d20\u5408\u7528\u65f6\u9700\u589e\u52a0\u5242\u91cf10-15%\u3002<\/p>\n

\u4e94\u3001\u7279\u6b8a\u4eba\u7fa4\u89e3\u51b3\u65b9\u6848
\n5.1 \u7d20\u98df\u5b55\u5987
\n\u63a8\u8350\u4f7f\u7528\u5fae\u751f\u7269\u53d1\u9175B12\uff08\u751f\u7269\u5229\u7528\u7387\u8fbe90%\uff09\uff0c\u6bcf\u65e5\u8865\u51452\u03bcg\u3002\u914d\u5408\u7ef4\u751f\u7d20C\uff0850mg\uff09\u4fc3\u8fdb\u5438\u6536\u3002<\/p>\n

5.2 \u80c3\u80a0\u75be\u75c5\u60a3\u8005
\n\u9009\u62e9\u4e9a\u5170\u80f6B12\uff08\u5438\u6536\u7387\uff1e80%\uff09\uff0c\u6bcf\u65e51mg\u5206\u4e09\u6b21\u670d\u7528\u3002\u907f\u514d\u4e0e\u80c6\u6c41\u9178\u87af\u5408\u5242\u540c\u65f6\u4f7f\u7528\u3002<\/p>\n

5.3 \u80be\u529f\u80fd\u4e0d\u5168\u8005
\n\u9700\u76d1\u6d4b\u8840B12\u6d53\u5ea6\uff0c\u8865\u5145\u5242\u91cf\u8c03\u6574\u4e3a\u5e38\u89c4\u91cf1\/3\u3002\u4e25\u91cd\u8005\u91c7\u7528\u9759\u8109\u6ce8\u5c04\uff08\u9700\u5728\u8425\u517b\u79d1\u76d1\u62a4\u4e0b\u8fdb\u884c\uff09\u3002<\/p>\n

\u516d\u3001\u4e34\u5e8a\u6848\u4f8b\u5206\u6790
\n\u6848\u4f8b1\uff1a32\u5c81\u5b55\u5987\uff0c\u7d20\u98df\u53f25\u5e74\uff0c\u5b558\u5468\u68c0\u6d4bB12\u6d53\u5ea6\u8fbe980pg\/mL\uff08\u8d85\u680754%\uff09\u3002\u7ecf\u8c03\u6574\u996e\u98df\u81f3\u6bcf\u65e5\u6444\u51652\u03bcg\u5f3a\u5316B12\uff0c\u914d\u5408\u53f6\u9178800\u03bcg\uff0c14\u5468\u590d\u67e5\u964d\u81f3620pg\/mL\uff0cHcy\u6c34\u5e73\u4ece12.3\u03bcmol\/L\u964d\u81f38.6\u03bcmol\/L\u3002<\/p>\n

\u6848\u4f8b2\uff1a38\u5c81\u598a\u5a20\u671f\u7cd6\u5c3f\u75c5\u5b55\u5987\uff0cB12\u6d53\u5ea61380pg\/mL\uff0c\u540c\u578b\u534a\u80f1\u6c28\u917815.8\u03bcmol\/L\u3002\u91c7\u7528500\u03bcg B12+500\u03bcg\u7532\u57fa\u53f6\u9178\u8054\u5408\u8865\u5145\uff0c28\u5468\u65f6Hcy\u964d\u81f39.2\u03bcmol\/L\uff0c\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u63a7\u5236\u57285.1%\u3002<\/p>\n

\n\u7ef4\u751f\u7d20B12\u7684\u5e73\u8861\u7ba1\u7406\u662f\u5b55\u671f\u8425\u517b\u7684\u5173\u952e\u73af\u8282\u3002\u5efa\u8bae\u5b55\u5987\u5b9a\u671f\u8fdb\u884c\u8840\u6e05B12\u5b9a\u91cf\u68c0\u6d4b\uff0c\u7ed3\u5408\u4e2a\u4f53\u60c5\u51b5\u9009\u62e9\u5b89\u5168\u8865\u5145\u65b9\u6848\u3002\u51fa\u73b0\u820c\u708e\u3001\u75b2\u52b3\u3001\u8bb0\u5fc6\u529b\u51cf\u9000\u7b49\u75c7\u72b6\u65f6\uff0c\u5e94\u53ca\u65f6\u5c31\u533b\u6392\u67e5\u8425\u517b\u4ee3\u8c22\u5f02\u5e38\u3002\u901a\u8fc7\u79d1\u5b66\u5e72\u9884\uff0c\u53ef\u4f7f\u80ce\u513f\u795e\u7ecf\u7ba1\u7578\u5f62\u98ce\u9669\u964d\u4f4e40%\uff0c\u65e9\u4ea7\u53d1\u751f\u7387\u4e0b\u964d25%\u3002<\/p>\n

\n
\"20260804125635_101\"<\/p>\n

\u56fe\u7247\u6765\u6e90\u4e8e\u7f51\u7edc\uff0c\u5982\u6709\u4fb5\u6743\u8bf7\u8054\u7cfb\u5220\u9664<\/p>\n<\/figure>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u7ef4\u751f\u7d20B12\u5b55\u5987\u8d85\u6807\uff1a\u80ce\u513f\u53d1\u80b2\u9690\u60a3\u4e0e\u79d1\u5b66\u5e72\u9884\u6307\u5357 \u5b55\u671f\u4fdd\u5065\u610f\u8bc6\u7684\u63d0\u5347\uff0c\u8d8a\u6765\u8d8a\u591a\u5b55\u5987\u5f00\u59cb\u5173\u6ce8\u8425\u517b\u8865\u5145\u95ee\u9898\u3002\u4f46\u636e\u300a […]<\/p>\n","protected":false},"author":1,"featured_media":10183,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[62,588,7651,1230,7650],"class_list":["post-10182","post","type-post","status-publish","format-standard","hentry","category-28","tag-1-1","tag-4-2","tag-7651","tag-1230","tag-7650"],"_links":{"self":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts\/10182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/comments?post=10182"}],"version-history":[{"count":0,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts\/10182\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/media\/10183"}],"wp:attachment":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/media?parent=10182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/categories?post=10182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/tags?post=10182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}