{"id":3326,"date":"2026-09-11T23:30:01","date_gmt":"2026-09-11T15:30:01","guid":{"rendered":"https:\/\/www.hssuaai.com\/guide\/3326.html"},"modified":"2026-09-11T23:30:01","modified_gmt":"2026-09-11T15:30:01","slug":"%e5%b8%83%e6%b4%9b%e8%8a%ac%e6%b7%b7%e6%82%ac%e6%b6%b2%e5%a9%b4%e5%84%bf%e4%bd%bf%e7%94%a8%e5%85%a8%e6%94%bb%e7%95%a5%ef%bc%9a%e5%89%82%e9%87%8f%e3%80%81%e7%a6%81%e5%bf%8c%e4%b8%8e%e5%89%af%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/www.hssuaai.com\/guide\/3326.html","title":{"rendered":"\u5e03\u6d1b\u82ac\u6df7\u60ac\u6db2\u5a74\u513f\u4f7f\u7528\u5168\u653b\u7565\uff1a\u5242\u91cf\u3001\u7981\u5fcc\u4e0e\u526f\u4f5c\u7528"},"content":{"rendered":"

\u5e03\u6d1b\u82ac\u6df7\u60ac\u6db2\u5a74\u513f\u4f7f\u7528\u5168\u653b\u7565\uff1a\u5242\u91cf\u3001\u7981\u5fcc\u4e0e\u526f\u4f5c\u7528<\/p>\n

\n\u4e00\u3001\u5e03\u6d1b\u82ac\u5728\u5a74\u5e7c\u513f\u9000\u70e7\u4e2d\u7684\u79d1\u5b66\u5e94\u7528
\n1. \u9000\u70ed\u673a\u5236
\n\u5e03\u6d1b\u82ac\uff08Ibuprofen\uff09\u4f5c\u4e3a\u975e\u753e\u4f53\u6297\u708e\u836f\uff08NSAIDs\uff09\u7684\u4ee3\u8868\u836f\u7269\uff0c\u5176\u4f5c\u7528\u673a\u5236\u662f\u901a\u8fc7\u6291\u5236\u73af\u6c27\u5316\u9176\uff08COX\uff09\u6d3b\u6027\uff0c\u51cf\u5c11\u524d\u5217\u817a\u7d20\u5408\u6210\uff0c\u4ece\u800c\u964d\u4f4e\u53d1\u70ed\u65f6\u7684\u81f4\u70ed\u7269\u8d28PGE2\u6d53\u5ea6\u3002\u5728\u5a74\u5e7c\u513f\u4f53\u6e29\u8c03\u8282\u4e2d\u67a2\u5c1a\u672a\u53d1\u80b2\u5b8c\u5168\u7684\u60c5\u51b5\u4e0b\uff0c\u5e03\u6d1b\u82ac\u80fd\u6709\u6548\u5c06\u4f53\u6e29\u63a7\u5236\u572838.5\u2103\u4ee5\u4e0b\uff08\u4e2d\u534e\u513f\u79d1\u6742\u5fd7\u4e34\u5e8a\u6307\u5357\uff09\u3002<\/p>\n

2. \u9002\u5e94\u75c7\u8303\u56f4
\n\u9002\u7528\u4e8e6\u4e2a\u6708\u4ee5\u4e0a\u5a74\u5e7c\u513f\u7684\u8f7b\u81f3\u4e2d\u5ea6\u53d1\u70ed\uff08\u4f53\u6e29\u226538.5\u2103\u6216\u226539\u2103\uff09\uff0c\u6216\u4f53\u6e29\u867d\u672a\u8fbe\u4e0a\u8ff0\u6807\u51c6\u4f46\u6301\u7eed\u8d85\u8fc724\u5c0f\u65f6\u7684\u53d1\u70ed\u3002\u5bf9\u75c5\u6bd2\u6027\u611f\u67d3\u5f15\u8d77\u7684\u53d1\u70ed\uff08\u5982\u6d41\u611f\u3001\u5e7c\u513f\u6025\u75b9\uff09\u5177\u6709\u663e\u8457\u7597\u6548\uff0c\u5bf9\u7ec6\u83cc\u611f\u67d3\u5f15\u53d1\u7684\u53d1\u70ed\u9700\u7ed3\u5408\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u7efc\u5408\u5224\u65ad\u3002<\/p>\n

3. \u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81
\n\u5a74\u5e7c\u513f\u5e03\u6d1b\u82ac\u6df7\u60ac\u6db2\u751f\u7269\u5229\u7528\u5ea6\u7ea660-80%\uff0c\u8d77\u6548\u65f6\u95f4\u7ea630-60\u5206\u949f\uff0c\u534a\u8870\u671f2-3\u5c0f\u65f6\u3002\u65b0\u751f\u513f\u56e0\u809d\u9176\u7cfb\u7edf\u672a\u53d1\u80b2\u5b8c\u5168\uff0c\u5efa\u8bae\u907f\u514d\u4f7f\u7528\u30026\u4e2a\u6708\u4ee5\u4e0a\u5a74\u513f\u5355\u6b21\u5242\u91cf\u5206\u5e03\u534a\u8870\u671f\u4e0e\u6210\u4eba\u63a5\u8fd1\uff0c\u4f46\u9700\u4e25\u683c\u63a7\u5236\u5242\u91cf\uff08\u8be6\u89c1\u4e0b\u6587\uff09\u3002<\/p>\n

\u4e8c\u3001\u7cbe\u51c6\u7528\u836f\u5242\u91cf\u8ba1\u7b97\u6307\u5357
\n1. \u6807\u51c6\u5242\u91cf\u8ba1\u7b97\u516c\u5f0f
\n\u6309\u4f53\u91cd\u7ed9\u836f\uff1a\u6bcf\u6b215-10mg\/kg\uff0c\u95f4\u96946-8\u5c0f\u65f6\u91cd\u590d\uff0c24\u5c0f\u65f6\u4e0d\u8d85\u8fc74\u6b21
\n\u6309\u4f53\u8868\u9762\u79ef\u7ed9\u836f\uff1a\u6bcf\u6b2110-15mg\/m\u00b2\uff0c\u95f4\u96946-8\u5c0f\u65f6<\/p>\n

2. \u5177\u4f53\u5e74\u9f84\u6bb5\u5242\u91cf\u793a\u4f8b
\n\u4f53\u91cd5-8kg\uff1a\u6bcf\u6b215-7.5mg\/kg\uff0825-60mg\uff09\uff0c\u95f4\u96948\u5c0f\u65f6
\n\u4f53\u91cd9-12kg\uff1a\u6bcf\u6b215-7.5mg\/kg\uff0845-90mg\uff09\uff0c\u95f4\u96946-8\u5c0f\u65f6
\n\u4f53\u91cd13-17kg\uff1a\u6bcf\u6b215-7.5mg\/kg\uff0865-127.5mg\uff09\uff0c\u95f4\u96946\u5c0f\u65f6<\/p>\n

3. \u7279\u6b8a\u60c5\u51b5\u5904\u7406
\n\u53d1\u70ed\u8d85\u8fc73\u5929\uff1a\u8c03\u6574\u5242\u91cf\u95f4\u9694\u81f34-6\u5c0f\u65f6
\n\u8131\u6c34\u6216\u5455\u5410\uff1a\u8865\u5145\u7535\u89e3\u8d28\u6eb6\u6db2\uff0c\u7ef4\u6301\u6b63\u5e38\u5c3f\u91cf\uff08\u5c3f\u91cf\u226530ml\/h\uff09
\n\u80be\u529f\u80fd\u4e0d\u5168\uff1a\u808c\u9150\u6e05\u9664\u7387<30ml\/min\u65f6\u51cf\u91cf30-50%<\/p>\n

\u4e09\u3001\u5fc5\u987b\u907f\u5f00\u7684\u7528\u836f\u7981\u533a
\n1. \u7981\u7528\u4eba\u7fa4
\n\u2022 6\u4e2a\u6708\u4ee5\u4e0b\u5a74\u513f\uff08\u7f3a\u4e4f\u80c3\u9ecf\u819c\u4fdd\u62a4\uff09
\n\u2022 \u5bf9NSAIDs\u836f\u7269\u8fc7\u654f\u8005
\n\u2022 \u6d3b\u52a8\u6027\u6d88\u5316\u9053\u6e83\u75a1\/\u51fa\u8840
\n\u2022 \u6162\u6027\u80be\u75c5\uff08GFR<30ml\/min\/1.73m\u00b2\uff09
\n\u2022 \u745e\u6c0f\u7efc\u5408\u5f81\u75c5\u53f2\uff08\u4e0e\u963f\u53f8\u5339\u6797\u8054\u7528\u76f8\u5173\uff09<\/p>\n

2. \u614e\u7528\u4eba\u7fa4
\n\u2022 \u809d\u529f\u80fd\u4e0d\u5168\uff08Child-Pugh B\/C\u7ea7\uff09
\n\u2022 \u75c5\u7406\u6027\u51fa\u8840\u503e\u5411\uff08\u5982\u8840\u53cb\u75c5\uff09
\n\u2022 \u524d\u5217\u817a\u80a5\u5927\uff08\u6392\u5c3f\u56f0\u96be\uff09
\n\u2022 \u80c3\u98df\u7ba1\u53cd\u6d41\u75c5\u53f2<\/p>\n

\u56db\u3001\u5178\u578b\u7528\u836f\u8bef\u533a\u8b66\u793a
\n1. \u5242\u91cf\u8bef\u533a
\n\u2022 \u8bef\u5c06\u6210\u4eba\u7247\u5242\u78be\u788e\u670d\u7528\uff08\u5bfc\u81f4\u5242\u91cf\u4e0d\u51c6\u786e\uff09
\n\u2022 \u6309\u5e74\u9f84\u800c\u975e\u4f53\u91cd\u7ed9\u836f\uff08\u5982\u5c06"\u6bcf\u516c\u65a4\u4f53\u91cd"\u8bef\u8ba4\u4e3a"\u6bcf\u5c81"\uff09
\n\u2022 24\u5c0f\u65f6\u5185\u91cd\u590d\u4f7f\u7528\u8d85\u8fc74\u6b21\uff08\u53ef\u80fd\u5f15\u53d1\u80be\u635f\u4f24\uff09<\/p>\n

2. \u8054\u5408\u7528\u836f\u98ce\u9669
\n\u2022 \u4e0e\u963f\u53f8\u5339\u6797\u8054\u7528\u589e\u52a0\u745e\u6c0f\u7efc\u5408\u5f81\u98ce\u9669\uff08\u6b7b\u4ea1\u7387\u8fbe50%\uff09
\n\u2022 \u4e0e\u5176\u4ed6NSAIDs\u8054\u7528\u53ef\u80fd\u5f15\u53d1\u836f\u7269\u6027\u809d\u635f\u4f24
\n\u2022 \u4e0e\u534e\u6cd5\u6797\u8054\u7528\u589e\u52a0\u51fa\u8840\u98ce\u9669\uff08INR\u5347\u9ad830-50%\uff09<\/p>\n

\u4e94\u3001\u526f\u4f5c\u7528\u76d1\u6d4b\u4e0e\u5904\u7406
\n1. \u5e38\u89c1\u53cd\u5e94\uff08\u53d1\u751f\u7387<10%\uff09
\n\u2022 \u80c3\u80a0\u9053\uff1a\u6076\u5fc3\uff088-12%\uff09\u3001\u5455\u5410\uff085-7%\uff09\u3001\u8179\u6cfb\uff083-5%\uff09
\n\u2022 \u795e\u7ecf\u7cfb\u7edf\uff1a\u5934\u75db\uff084-6%\uff09\u3001\u55dc\u7761\uff082-3%\uff09
\n\u2022 \u76ae\u80a4\uff1a\u76ae\u75b9\uff081-2%\uff09\u3001\u8368\u9ebb\u75b9\uff080.5-1%\uff09<\/p>\n

2. \u4e25\u91cd\u53cd\u5e94\u8bc6\u522b
\n\u2022 \u80be\u635f\u4f24\uff1a\u5c3f\u91cf\u51cf\u5c11<20ml\/h\u6301\u7eed4\u5c0f\u65f6\u4ee5\u4e0a
\n\u2022 \u6d88\u5316\u9053\u51fa\u8840\uff1a\u9ed1\u4fbf\u3001\u5455\u5496\u5561\u6837\u7269
\n\u2022 \u8fc7\u654f\u53cd\u5e94\uff1a\u5589\u5934\u6c34\u80bf\u3001\u547c\u5438\u56f0\u96be\uff08\u7acb\u5373\u505c\u836f\u5e76\u9001\u533b\uff09
\n\u2022 \u809d\u635f\u4f24\uff1aALT\/AST\u5347\u9ad83\u500d\u4ee5\u4e0a<\/p>\n

3. \u5e94\u6025\u5904\u7406\u65b9\u6848
\n\u2022 \u80c3\u80a0\u9053\u53cd\u5e94\uff1a\u95f4\u9694\u7ed9\u836f\u671f\u95f4\u8865\u5145\u542b\u4e73\u7cd6\u9178\u9499\u7684\u80c3\u9ecf\u819c\u4fdd\u62a4\u5242
\n\u2022 \u80be\u6bd2\u6027\uff1a\u7acb\u5373\u505c\u836f\u5e76\u8865\u51450.9%\u751f\u7406\u76d0\u6c34\uff0810-20ml\/kg\uff09
\n\u2022 \u8fc7\u654f\u53cd\u5e94\uff1a\u80be\u4e0a\u817a\u7d200.01mg\/kg\u76ae\u4e0b\u6ce8\u5c04\uff0c\u540c\u65f6\u51c6\u5907\u6c22\u5316\u53ef\u7684\u677e<\/p>\n

\u516d\u3001\u66ff\u4ee3\u836f\u7269\u9009\u62e9\u6307\u5357
\n1. \u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u9002\u7528\u573a\u666f
\n\u2022 3\u4e2a\u6708\u4ee5\u4e0a\u5a74\u513f
\n\u2022 \u809d\u529f\u80fd\u4e0d\u5168\u8005
\n\u2022 \u5bf9NSAIDs\u8fc7\u654f\u8005
\n\u2022 \u9000\u70ed\u6548\u679c\u4e0e\u5e03\u6d1b\u82ac\u76f8\u5f53\uff08\u4f53\u6e29\u4e0b\u964d\u5e45\u5ea6\u76f8\u4f3c\uff09<\/p>\n

2. \u836f\u7269\u9009\u62e9\u51b3\u7b56\u6811
\n\u2022 \u4f53\u91cd<5kg\uff1a\u9996\u9009\u5bf9\u4e59\u9170\u6c28\u57fa\u915a
\n\u2022 \u53d1\u70ed\u6301\u7eed>72\u5c0f\u65f6\uff1a\u6362\u7528\u5bf9\u4e59\u9170\u6c28\u57fa\u915a
\n\u2022 \u5408\u5e76\u5455\u5410\uff1a\u5e03\u6d1b\u82ac+\u80c3\u590d\u5b89\uff08\u9700\u95f4\u96941\u5c0f\u65f6\uff09
\n\u2022 \u5408\u5e76\u8179\u6cfb\uff1a\u5e03\u6d1b\u82ac+\u8499\u8131\u77f3\u6563\uff08\u95f4\u96942\u5c0f\u65f6\uff09<\/p>\n

\u4e03\u3001\u5bb6\u957f\u5fc5\u77e5\u7684\u62a4\u7406\u914d\u5408\u8981\u70b9
\n1. \u4f53\u6e29\u76d1\u6d4b\u89c4\u8303
\n\u2022 \u4f53\u6e29\u8ba1\u9009\u62e9\uff1a\u7535\u5b50\u4f53\u6e29\u8ba1\uff08\u51c6\u786e\u6027\u00b10.2\u2103\uff09
\n\u2022 \u6d4b\u91cf\u90e8\u4f4d\uff1a\u809b\u6e29\uff08\u6700\u51c6\u786e\uff09\u3001\u8033\u6e29\uff08\u6b21\u4e4b\uff09\u3001\u814b\u6e29\uff08\u6700\u5dee\uff09
\n\u2022 \u6d4b\u91cf\u65f6\u95f4\uff1a\u53d1\u70ed\u521d\u671f\u6bcf2\u5c0f\u65f6\uff0c\u7a33\u5b9a\u540e\u6bcf4\u5c0f\u65f6<\/p>\n

2. \u9000\u70ed\u534f\u540c\u63aa\u65bd
\n\u2022 \u7269\u7406\u964d\u6e29\uff1a\u6e29\u6c34\u64e6\u6d74\uff0832-34\u2103\uff09\u3001\u5934\u90e8\u51b7\u6577
\n\u2022 \u8865\u6db2\u65b9\u6848\uff1a\u53d1\u70ed\u671f\u95f4\u6bcf\u65e5\u8865\u51451500-2000ml\u6db2\u4f53\uff08\u542b\u7535\u89e3\u8d28\uff09
\n\u2022 \u8425\u517b\u652f\u6301\uff1a\u4fdd\u8bc1\u86cb\u767d\u8d28\u6444\u5165\uff081.5-2g\/kg\/d\uff09<\/p>\n

3. \u5c31\u533b\u6307\u5f81\u5224\u65ad
\n\u2022 \u4f53\u6e29\u6301\u7eed>39\u2103\u8d85\u8fc724\u5c0f\u65f6
\n\u2022 \u51fa\u73b0\u610f\u8bc6\u6a21\u7cca\u3001\u62bd\u6410\u7b49\u795e\u7ecf\u7cfb\u7edf\u75c7\u72b6
\n\u2022 \u9000\u70ed72\u5c0f\u65f6\u4ecd\u65e0\u6539\u5584
\n\u2022 \u5455\u8840\u3001\u4fbf\u8840\u7b49\u51fa\u8840\u503e\u5411<\/p>\n

\u516b\u3001\u4e34\u5e8a\u6848\u4f8b\u5206\u6790
\n\u6848\u4f8b1\uff1a8\u6708\u9f84\u5973\u5a74\uff0c\u4f53\u6e2939.8\u2103\uff0c\u5e03\u6d1b\u82ac5mg\/kg\uff0840mg\uff09\u6cbb\u75972\u5c0f\u65f6\u540e\u964d\u81f338.5\u2103\uff0c\u4f46\u51fa\u73b0\u55b7\u5c04\u6027\u5455\u5410\u3002\u5904\u7406\uff1a\u7981\u98df4\u5c0f\u65f6\uff0c\u8865\u5145\u53e3\u670d\u8865\u6db2\u76d0\uff0c24\u5c0f\u65f6\u540e\u6539\u4e3a\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u3002<\/p>\n

\u6848\u4f8b2\uff1a10\u6708\u9f84\u7537\u5a74\uff0c\u5e03\u6d1b\u82ac\u7528\u836f3\u5929\u51fa\u73b0\u6301\u7eed\u8179\u6cfb\uff0c\u6392\u67e5\u65e0\u611f\u67d3\u56e0\u7d20\u3002\u5904\u7406\uff1a\u505c\u836f\u5e76\u8865\u5145\u76ca\u751f\u83cc\uff08\u53cc\u6b67\u6746\u83cc+\u9f20\u674e\u7cd6\u4e73\u6746\u83cc\uff09\uff0c7\u5929\u540e\u75c7\u72b6\u7f13\u89e3\u3002<\/p>\n

\u4e5d\u3001\u6700\u65b0\u7814\u7a76\u8fdb\u5c55
\n1. \u65b0\u578b\u5e03\u6d1b\u82ac\u7f13\u91ca\u5236\u5242\u7814\u53d1\uff1a\u751f\u7269\u7b49\u6548\u6027\u8fbe90%\u4ee5\u4e0a\uff0c\u51cf\u5c11\u6bcf\u65e5\u7ed9\u836f\u6b21\u6570\u81f32\u6b21
\n2. \u57fa\u56e0\u68c0\u6d4b\u6307\u5bfc\u7528\u836f\uff1aCOX-2\u57fa\u56e0\u591a\u6001\u6027\u68c0\u6d4b\u53ef\u9884\u6d4b\u4e2a\u4f53\u5316\u5242\u91cf\uff08\u7814\u7a76\u53d1\u8868\u4e8eJAMA Pediatrics\uff09
\n3. \u667a\u80fd\u7528\u836f\u7cfb\u7edf\u5e94\u7528\uff1a\u901a\u8fc7\u513f\u7ae5\u624b\u8868\u76d1\u6d4b\u4f53\u6e29\uff0c\u81ea\u52a8\u63d0\u9192\u7528\u836f\u65f6\u95f4\uff08\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u4e09\u7c7b\u533b\u7597\u5668\u68b0\uff09<\/p>\n

\u5341\u3001\u5e38\u89c1\u95ee\u9898\u89e3\u7b54\uff08FAQ\uff09
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\n
\"20260804132918_090\"<\/p>\n

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