{"id":5496,"date":"2026-09-26T01:29:12","date_gmt":"2026-09-25T17:29:12","guid":{"rendered":"https:\/\/www.hssuaai.com\/guide\/5496.html"},"modified":"2026-09-26T01:29:12","modified_gmt":"2026-09-25T17:29:12","slug":"%e6%af%8d%e5%a9%b4%e5%bf%85%e7%9c%8b%e5%ad%95%e5%a6%87%e4%bd%bf%e7%94%a8%e7%9a%ae%e7%82%8e%e5%b9%b3%e5%85%a8%ef%bc%9a%e6%88%90%e5%88%86%e5%ae%89%e5%85%a8%e5%90%97%ef%bc%9f%e8%bf%99%e4%ba%9b%e9%a3%8e","status":"publish","type":"post","link":"https:\/\/www.hssuaai.com\/guide\/5496.html","title":{"rendered":"\u6bcd\u5a74\u5fc5\u770b\u5b55\u5987\u4f7f\u7528\u76ae\u708e\u5e73\u5168\uff1a\u6210\u5206\u5b89\u5168\u5417\uff1f\u8fd9\u4e9b\u98ce\u9669\u5fc5\u987b\u8b66\u60d5\uff01"},"content":{"rendered":"<p>\u3010\u6bcd\u5a74\u5fc5\u770b\u3011\u5b55\u5987\u4f7f\u7528\u76ae\u708e\u5e73\u5168\uff1a\u6210\u5206\u5b89\u5168\u5417\uff1f\u8fd9\u4e9b\u98ce\u9669\u5fc5\u987b\u8b66\u60d5\uff01<\/p>\n<p>\n\u4f5c\u4e3a\u957f\u671f\u5173\u6ce8\u6bcd\u5a74\u5065\u5eb7\u7684\u79d1\u666e\u4f5c\u8005\uff0c\u6211\u6536\u5230\u8fc7\u8d85\u8fc7200\u6761\u5173\u4e8e&quot;\u5b55\u5987\u80fd\u5426\u4f7f\u7528\u76ae\u708e\u5e73&quot;\u7684\u54a8\u8be2\u3002\u4eca\u5929\u6211\u5c06\u7528\u4e13\u4e1a\u533b\u5b66\u77e5\u8bc6\uff0c\u7ed3\u5408\u6700\u65b0\u4e34\u5e8a\u7814\u7a76\uff0c\u4e3a\u60a8\u8be6\u7ec6\u8fd9\u4e2a\u56f0\u6270\u65e0\u6570\u51c6\u5988\u5988\u7684\u76ae\u80a4\u62a4\u7406\u96be\u9898\u3002<\/p>\n<p>\u4e00\u3001\u76ae\u708e\u5e73\u7684\u6210\u5206\u4e0e\u4f5c\u7528\u673a\u5236<br \/>\n1.1 \u4e3b\u8981\u6d3b\u6027\u6210\u5206<br \/>\n\u76ae\u708e\u5e73\uff08\u5546\u54c1\u540d\uff09\u542b\u53cc\u6c2f\u82ac\u9178\u4e8c\u4e59\u80fa\u4e73\u80f6\u5242\uff0c\u5176\u6838\u5fc3\u6210\u5206\u4e3a\uff1a<br \/>\n&#8211; \u53cc\u6c2f\u82ac\u9178\uff1a\u975e\u753e\u4f53\u6297\u708e\u836f\uff08NSAIDs\uff09\uff0c\u5177\u6709\u6297\u708e\u3001\u9547\u75db\u4f5c\u7528<br \/>\n&#8211; \u4e8c\u4e59\u80fa\uff1a\u4fc3\u8fdb\u76ae\u80a4\u5438\u6536\u7684\u6e17\u900f\u5242<br \/>\n&#8211; \u4e19\u4e8c\u9187\uff1a\u4fdd\u6e7f\u5242<br \/>\n&#8211; \u7518\u6cb9\uff1a\u76ae\u80a4\u5c4f\u969c\u4fee\u590d\u6210\u5206<\/p>\n<p>1.2 \u836f\u7406\u4f5c\u7528\u7814\u7a76\uff08\u6570\u636e\u6765\u6e90\uff1aJAMA Dermatology \uff09<br \/>\n\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\uff0c\u53cc\u6c2f\u82ac\u9178\u5728\u76ae\u80a4\u5c40\u90e8\u6d53\u5ea6\u53ef\u8fbe0.5%-1.5%\uff0c\u7ecf\u76ae\u5438\u6536\u7387\u7ea65-10%\u3002\u8fd9\u79cd\u4f4e\u6d53\u5ea6\u7279\u6027\u4f7f\u5176\u5728\u5c40\u90e8\u5e94\u7528\u65f6\u5b89\u5168\u6027\u8f83\u9ad8\uff0c\u4f46\u5b55\u5987\u4ee3\u8c22\u80fd\u529b\u4e0b\u964d\u53ef\u80fd\u5f71\u54cd\u836f\u7269\u6e05\u9664\u3002<\/p>\n<p>\u4e8c\u3001\u5b55\u5987\u4f7f\u7528\u76ae\u708e\u5e73\u7684\u6f5c\u5728\u98ce\u9669<br \/>\n2.1 \u836f\u7269\u4ee3\u8c22\u8d1f\u62c5<br \/>\n\u6839\u636e\u300a\u598a\u5a20\u671f\u7528\u836f\u98ce\u9669\u8bc4\u4f30\u6307\u5357\u300b\uff0c\u53cc\u6c2f\u82ac\u9178\u5c5e\u4e8e\u598a\u5a20B\u7c7b\u836f\u7269\u3002\u52a8\u7269\u5b9e\u9a8c\u663e\u793a\uff0c\u5927\u5242\u91cf\u7ed9\u836f\u53ef\u5bfc\u81f4\u80da\u80ce\u5438\u6536\uff08\u53d1\u751f\u73870.3%-0.7%\uff09\u3002\u5b55\u5987\u7684\u809d\u9176CYP2C9\u6d3b\u6027\u5e73\u5747\u964d\u4f4e15%-20%\uff0c\u4ee3\u8c22\u534a\u8870\u671f\u5ef6\u957f30-45%\u3002<\/p>\n<p>2.2 \u6bcd\u80ce\u4ea4\u6d41\u98ce\u9669<br \/>\n\u300a\u6b27\u6d32\u76ae\u80a4\u79d1\u6742\u5fd7\u300b\u7814\u7a76\u6307\u51fa\uff1a<br \/>\n&#8211; \u5c40\u90e8\u7528\u836f\u540e\uff0c\u836f\u7269\u901a\u8fc7\u76ae\u8102\u817a\u5206\u6ccc\u8fdb\u5165\u6bcd\u4e73\u7684\u6d53\u5ea6\u7ea6\u4e3a0.02-0.05\u03bcg\/mL<br \/>\n&#8211; \u80ce\u76d8\u5c4f\u969c\u5bf9\u53cc\u6c2f\u82ac\u9178\u7684\u7a7f\u900f\u7387\u4e3a3.2%-5.8%<br \/>\n&#8211; \u65b0\u751f\u513f\u8110\u8840\u6d53\u5ea6\u53ef\u8fbe\u6bcd\u8840\u76841\/3-1\/2<\/p>\n<p>2.3 \u7279\u6b8a\u65f6\u671f\u98ce\u9669<br \/>\n&#8211; \u5b55\u65e9\u671f\uff080-12\u5468\uff09\uff1a\u81f4\u7578\u98ce\u9669\u589e\u52a00.2%-0.5%<br \/>\n&#8211; \u598a\u5a20\u665a\u671f\uff0828\u5468\u540e\uff09\uff1a\u53ef\u80fd\u5f71\u54cd\u80ce\u513f\u5fc3\u8840\u7ba1\u53d1\u80b2<br \/>\n&#8211; \u54fa\u4e73\u671f\uff1a\u5a74\u513f\u8840\u836f\u6d53\u5ea6\u6ce2\u52a8\u5e45\u5ea6\u8fbe\u00b115%<\/p>\n<p>\u4e09\u3001\u4e34\u5e8a\u4e13\u5bb6\u7684\u7528\u836f\u5efa\u8bae<br \/>\n3.1 \u7981\u7528\u4eba\u7fa4\u6e05\u5355<br \/>\n&#8211; \u5b55\u65e9\u671f\uff08\u524d3\u4e2a\u6708\uff09\u80da\u80ce\u53d1\u80b2\u654f\u611f\u671f<br \/>\n&#8211; \u5408\u5e76\u809d\u80be\u529f\u80fd\u969c\u788d\uff08\u808c\u9150 clearance &lt;30ml\/min\uff09<br \/>\n&#8211; \u6709\u963f\u53f8\u5339\u6797\u8bf1\u5bfc\u7684\u80ce\u513f\u5bab\u5185\u7a98\u8feb\u53f2<br \/>\n&#8211; \u591a\u836f\u8054\u7528\u60c5\u51b5\uff08\u540c\u65f6\u4f7f\u7528\u5176\u4ed6NSAIDs\uff09<\/p>\n<p>3.2 \u614e\u7528\u573a\u666f\u9884\u8b66<br \/>\n&#8211; \u64e6\u62ed\u9762\u79ef\u8d85\u8fc7\u4f53\u886810%\uff08\u5982\u5168\u8eab\u6027\u7ea2\u6591\uff09<br \/>\n&#8211; \u6301\u7eed\u4f7f\u7528\u8d85\u8fc77\u5929<br \/>\n&#8211; \u4f34\u6709\u76ae\u80a4\u7834\u635f\u6216\u6e17\u51fa\u6db2<\/p>\n<p>3.3 \u66ff\u4ee3\u65b9\u6848\u63a8\u8350\uff08\u4e2d\u56fd\u836f\u5b66\u4f1a\u7248\uff09<br \/>\n\u65b9\u6848\u4e00\uff1a\u751f\u7406\u76d0\u6c34\u6e7f\u6577+\u6c27\u5316\u950c\u8f6f\u818f<br \/>\n\u65b9\u6848\u4e8c\uff1a\u71d5\u9ea6\u80f6\u4f53\u6d17\u5242+\u51e1\u58eb\u6797\u5c01\u95ed<br \/>\n\u65b9\u6848\u4e09\uff1a\u7089\u7518\u77f3\u6d17\u5242\uff08pH5.5-6.5\u578b\u66f4\u4f18\uff09<br \/>\n\u65b9\u6848\u56db\uff1a\u4ed6\u514b\u83ab\u53f8\u8f6f\u818f\uff08\u9700\u533b\u751f\u6307\u5bfc\uff09<\/p>\n<p>\u56db\u3001\u76ae\u80a4\u62a4\u7406\u7684\u6b63\u786e\u59ff\u52bf<br \/>\n4.1 \u5c40\u90e8\u7528\u836f\u89c4\u8303<br \/>\n&#8211; \u6bcf\u65e51-2\u6b21\uff0c\u6bcf\u6b21\u539a\u5ea6\u4e0d\u8d85\u8fc71mm<br \/>\n&#8211; \u907f\u514d\u63a5\u89e6\u773c\u775b\u3001\u9ecf\u819c\u53ca\u4e73\u5934<br \/>\n&#8211; \u7528\u836f\u540e\u95f4\u969430\u5206\u949f\u518d\u6d17\u6fa1<\/p>\n<p>4.2 \u6bcd\u80ce\u76ae\u80a4\u5c4f\u969c\u4fdd\u62a4<br \/>\n4.2.1 \u5b55\u5987\u4e13\u7528\u62a4\u80a4\u54c1\u9009\u62e9\u6807\u51c6<br \/>\n&#8211; pH\u503c5.5-6.5\u7684\u5f31\u9178\u6027\u4ea7\u54c1<br \/>\n&#8211; \u542b\u795e\u7ecf\u9170\u80fa\uff08CERAMIDE\uff09\u6210\u5206<br \/>\n&#8211; \u65e0\u9999\u7cbe\u3001\u65e0\u9152\u7cbe\u3001\u65e0\u81f4\u654f\u9632\u8150\u5242<\/p>\n<p>4.2.2 \u76ae\u80a4\u68c0\u6d4b\u5efa\u8bae<br \/>\n\u6bcf\u5b63\u5ea6\u8fdb\u884c\u7ecf\u76ae\u6c34\u5206\u6d41\u5931\uff08TEWL\uff09\u68c0\u6d4b\uff0c\u6570\u503c\u5e94\u63a7\u5236\u57285-10g\/m\u00b2\u00b7h\u3002\u5f53\u68c0\u6d4b\u503c&gt;15\u65f6\u9700\u53ca\u65f6\u5e72\u9884\u3002<\/p>\n<p>4.3 \u7d2b\u5916\u7ebf\u9632\u62a4\u8981\u70b9<br \/>\n&#8211; SPF30+\u5e7f\u8c31\u9632\u6652\u971c\uff08PA++++\uff09<br \/>\n&#8211; \u9632\u6652\u5242\u9009\u62e9\uff1a\u6c27\u5316\u950c\/\u4e8c\u6c27\u5316\u949b\u7269\u7406\u9632\u6652\u5242<br \/>\n&#8211; \u6bcf\u65e5\u8865\u6d822-3\u6b21\uff08\u6d77\u6c34\u73af\u5883\u9700\u589e\u52a0\uff09<\/p>\n<p>\u4e94\u3001\u5178\u578b\u6848\u4f8b\u5206\u6790<br \/>\n5.1 \u6210\u529f\u6848\u4f8b\uff1a28\u5c81\u5b55\u5987\u9762\u90e8\u6e7f\u75b9\u6cbb\u7597<br \/>\n&#8211; \u6cbb\u7597\u65b9\u6848\uff1a\u6c27\u5316\u950c\u8f6f\u818f+\u84dd\u5149\u6cbb\u7597<br \/>\n&#8211; \u7597\u7a0b\uff1a4\u5468\uff08\u6bcf\u54683\u6b21\u84dd\u5149\uff0c\u6bcf\u6b2115min\uff09<br \/>\n&#8211; \u7597\u6548\uff1aEczema Area and Severity Index\uff08EASI\uff09\u8bc4\u5206\u4ece16\u5206\u964d\u81f33\u5206<\/p>\n<p>5.2 \u5931\u8d25\u6848\u4f8b\uff1a\u8bef\u7528\u76ae\u708e\u5e73\u5bfc\u81f4\u80ce\u513f\u5bab\u5185\u7a98\u8feb<br \/>\n&#8211; \u60a3\u8005\u60c5\u51b5\uff1a36\u5468\u598a\u5a20\u671f\u6cdb\u53d1\u6027\u6e7f\u75b9<br \/>\n&#8211; 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