{"id":8898,"date":"2026-10-18T18:29:01","date_gmt":"2026-10-18T10:29:01","guid":{"rendered":"https:\/\/www.hssuaai.com\/guide\/8898.html"},"modified":"2026-10-18T18:29:01","modified_gmt":"2026-10-18T10:29:01","slug":"%e5%ad%95%e6%9c%9f%e8%a1%80%e8%b1%a1%e5%bc%82%e5%b8%b8%e4%bc%9a%e5%bd%b1%e5%93%8d%e8%83%8e%e5%84%bf%e5%90%97%ef%bc%9f%e4%ba%a7%e6%a3%80%e5%bf%85%e7%9c%8b%e8%a1%80%e5%b8%b8%e8%a7%84%e6%8c%87%e6%a0%87","status":"publish","type":"post","link":"https:\/\/www.hssuaai.com\/guide\/8898.html","title":{"rendered":"\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u4f1a\u5f71\u54cd\u80ce\u513f\u5417\uff1f\u4ea7\u68c0\u5fc5\u770b\u8840\u5e38\u89c4\u6307\u6807\u89e3\u8bfb\u4e0e\u5e94\u5bf9\u63aa\u65bd\uff08\u9644\u68c0\u67e5\u6e05\u5355\uff09"},"content":{"rendered":"

\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u4f1a\u5f71\u54cd\u80ce\u513f\u5417\uff1f\u4ea7\u68c0\u5fc5\u770b\u8840\u5e38\u89c4\u6307\u6807\u89e3\u8bfb\u4e0e\u5e94\u5bf9\u63aa\u65bd\uff08\u9644\u68c0\u67e5\u6e05\u5355\uff09<\/p>\n

\n\u4e00\u3001\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u7684\u5e38\u89c1\u8868\u73b0\u4e0e\u6f5c\u5728\u98ce\u9669
\n\uff08\uff1a\u5b55\u671f\u8840\u5e38\u89c4\u68c0\u67e5 \u80ce\u513f\u5065\u5eb7 \u4ea7\u68c0\u6ce8\u610f\u4e8b\u9879\uff09<\/p>\n

\u5728\u5b55\u4ea7\u533b\u5b66\u4e2d\uff0c\u8840\u6db2\u68c0\u67e5\u662f\u8bc4\u4f30\u6bcd\u5a74\u5065\u5eb7\u7684\u91cd\u8981\u7a97\u53e3\u3002\u6839\u636e\u56fd\u5bb6\u536b\u5065\u59d4\u300a\u5b55\u4ea7\u671f\u5065\u5eb7\u7ba1\u7406\u89c4\u8303\u300b\uff0c\u5b55\u5987\u5728\u5b55\u65e9\u671f\u3001\u4e2d\u671f\u3001\u665a\u671f\u5404\u9700\u8fdb\u884c\u81f3\u5c113\u6b21\u8840\u5e38\u89c4\u76d1\u6d4b\u3002\u6570\u636e\u663e\u793a\uff0c\u7ea635%\u7684\u5b55\u5987\u5728\u5b55\u671f\u4f1a\u51fa\u73b0\u4e0d\u540c\u7a0b\u5ea6\u7684\u8840\u8c61\u5f02\u5e38\uff0c\u5176\u4e2d\u4ee5\u767d\u7ec6\u80de\u5347\u9ad8\uff08\u767d\u7ec6\u80de\u589e\u591a\u75c7\uff09\u6700\u4e3a\u5e38\u89c1\uff0c\u5360\u6bd4\u8fbe28.6%\u3002<\/p>\n

1. \u8840\u7ec6\u80de\u5f02\u5e38\u7684\u5178\u578b\u75c7\u72b6
\n– \u767d\u7ec6\u80de\u8ba1\u6570\uff08WBC\uff09\uff1a\u6b63\u5e38\u8303\u56f4\uff084.0-10.0\uff09\u00d710^9\/L\uff0c\u82e5\u6301\u7eed\uff1e11.0\u00d710^9\/L\u9700\u8b66\u60d5\u611f\u67d3\u6216\u708e\u75c7
\n– \u7ea2\u7ec6\u80de\u8ba1\u6570\uff08RBC\uff09\uff1a\u6b63\u5e38\u503c\uff083.8-5.1\uff09\u00d710^12\/L\uff0c\uff1c3.5\u00d710^12\/L\u63d0\u793a\u8d2b\u8840\u98ce\u9669
\n– \u8840\u5c0f\u677f\u8ba1\u6570\uff08PLT\uff09\uff1a\u6b63\u5e38\u503c\uff08150-450\uff09\u00d710^9\/L\uff0c\uff1c100\u00d710^9\/L\u9700\u7d27\u6025\u5e72\u9884<\/p>\n

2. \u6bcd\u80ce\u53cc\u65b9\u7684\u8fde\u9501\u53cd\u5e94
\n\uff08\uff1a\u80ce\u513f\u53d1\u80b2\u5f02\u5e38 \u5b55\u671f\u8425\u517b\u7ba1\u7406\uff09
\n\u5f53\u5b55\u5987\u51fa\u73b0\u6301\u7eed\u6027\u7684\u767d\u7ec6\u80de\u5347\u9ad8\uff08\u5982\u7ec6\u83cc\u6027\u9634\u9053\u708e\u5f15\u53d1\u7684WBC\uff1e12\u00d710^9\/L\uff09\uff0c\u53ef\u80fd\u901a\u8fc7\u80ce\u76d8\u5c4f\u969c\u5bfc\u81f4\u80ce\u513f\u8110\u8840\u4e2d\u767d\u7ec6\u80de\u6d53\u5ea6\u5347\u9ad8\u3002\u4e34\u5e8a\u7814\u7a76\u8bc1\u5b9e\uff0c\u5b55\u665a\u671fWBC\uff1e15\u00d710^9\/L\u7684\u5b55\u5987\uff0c\u5176\u80ce\u513f\u7a98\u8feb\u53d1\u751f\u7387\u8f83\u6b63\u5e38\u7ec4\u9ad8\u51fa47.3%\u3002<\/p>\n

\u4e8c\u3001\u8840\u8c61\u5f02\u5e38\u7684\u56db\u5927\u7c7b\u578b
\n\uff08\uff1a\u5b55\u671f\u8840\u5e38\u89c4\u6307\u6807\u89e3\u8bfb \u4ea7\u524d\u8bca\u65ad\uff09<\/p>\n

1. \u767d\u7ec6\u80de\u589e\u591a\u75c7\uff08WBC\u2191\uff09
\n– \u5e38\u89c1\u8bf1\u56e0\uff1a\u7ec6\u83cc\u6027\u9634\u9053\u708e\uff08\u536062%\uff09\u3001\u5c3f\u8def\u611f\u67d3\uff0828%\uff09\u3001\u598a\u5a20\u671f\u9ad8\u8840\u538b\uff0815%\uff09
\n– \u80ce\u513f\u5f71\u54cd\uff1a\u53ef\u80fd\u5f15\u53d1\u80ce\u513f\u80ba\u8868\u9762\u6d3b\u6027\u7269\u8d28\u5206\u6ccc\u51cf\u5c11\uff0c\u65e9\u4ea7\u98ce\u9669\u589e\u52a02.4\u500d
\n– \u8bca\u7597\u65b9\u6848\uff1a\u9700\u7ed3\u5408C\u53cd\u5e94\u86cb\u767d\uff08CRP\uff09\u548c\u964d\u9499\u7d20\u539f\uff08PCT\uff09\u8fdb\u884c\u9274\u522b\u8bca\u65ad<\/p>\n

2. \u7ea2\u7ec6\u80de\u51cf\u5c11\u75c7\uff08RBC\u2193\uff09
\n– \u5178\u578b\u7279\u5f81\uff1aHb\uff1c110g\/L\uff0c\u8840\u6e05\u94c1\u86cb\u767d\uff1c30\u03bcg\/L
\n– \u5e76\u53d1\u75c7\u94fe\uff1a\u80ce\u513f\u8d2b\u8840\u2192\u80ce\u76d8\u4f9b\u6c27\u4e0d\u8db3\u2192\u751f\u957f\u8fdf\u7f13\uff08\u53d1\u751f\u7387\u8fbe34.7%\uff09
\n– \u5904\u7406\u539f\u5219\uff1a\u94c1\u5242\u6cbb\u7597\u6709\u6548\u738791.2%\uff0c\u9700\u76d1\u6d4b\u8840\u6e05\u94c1\u9971\u548c\u5ea6<\/p>\n

3. \u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08PLT\u2193\uff09
\n– \u5371\u9669\u9608\u503c\uff1a\uff1c50\u00d710^9\/L\uff08\u9700\u8f93\u6ce8\u8840\u5c0f\u677f\uff09
\n– \u6bcd\u80ce\u5173\u8054\uff1a\u598a\u5a20\u671fPLT\uff1c80\u00d710^9\/L\u65f6\uff0c\u80ce\u513f\u9885\u5185\u51fa\u8840\u98ce\u9669\u589e\u52a05.8\u500d
\n– \u9884\u9632\u63aa\u65bd\uff1a\u7ef4\u751f\u7d20K4 10mg\/d+\u53f6\u91780.4mg\/d\u8054\u5408\u6cbb\u7597<\/p>\n

4. \u6dcb\u5df4\u7ec6\u80de\u589e\u591a\u75c7\uff08Lym\u2191\uff09
\n– \u7279\u6b8a\u8868\u73b0\uff1aT\u6dcb\u5df4\u7ec6\u80de\u7edd\u5bf9\u503c\uff1e2.0\u00d710^9\/L
\n– \u9884\u540e\u5173\u8054\uff1a\u4e0e\u80ce\u513f\u5148\u5929\u6027\u98ce\u75b9\u7efc\u5408\u5f81\u6b63\u76f8\u5173\uff08OR=3.17\uff09
\n– \u5e72\u9884\u5efa\u8bae\uff1a\u5e72\u6270\u7d20\u03b1\u8054\u5408\u80f8\u817a\u80bd\u6cbb\u7597<\/p>\n

\u4e09\u3001\u4ea7\u68c0\u4e2d\u7684\u8840\u8c61\u7ba1\u7406\u7b56\u7565
\n\uff08\uff1a\u5b55\u671f\u4fdd\u5065 \u8840\u5e38\u89c4\u89e3\u8bfb\uff09<\/p>\n

1. \u68c0\u67e5\u65f6\u673a\u4e0e\u9891\u7387
\n– \u5b55\u65e9\u671f\uff0812-13\u5468\uff09\uff1a\u57fa\u7840\u8840\u5e38\u89c4+\u94c1\u4ee3\u8c22\u56db\u9879
\n– \u5b55\u4e2d\u671f\uff0828\u5468\uff09\uff1a\u8840\u5e38\u89c4+\u94c1\u86cb\u767d+\u53f6\u9178\u6c34\u5e73
\n– \u5b55\u665a\u671f\uff0834\u5468\uff09\uff1a\u8840\u5e38\u89c4+\u51dd\u8840\u529f\u80fd+\u80ce\u513f\u8110\u8840\u7a7f\u523a\u6307\u5f81\u8bc4\u4f30<\/p>\n

2. \u5f02\u5e38\u503c\u7684\u4e34\u5e8a\u5904\u7406\u6d41\u7a0b
\n\uff08\u9644\uff1a\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u5904\u7406\u6d41\u7a0b\u56fe\uff09<\/p>\n

\uff08\u6b64\u5904\u63d2\u5165\u6d41\u7a0b\u56fe\uff1a\u8840\u8c61\u5f02\u5e38\u2192\u75c5\u56e0\u6392\u67e5\u2192\u6bcd\u80ce\u98ce\u9669\u8bc4\u4f30\u2192\u4e2a\u4f53\u5316\u65b9\u6848\uff09<\/p>\n

\u56db\u3001\u5c45\u5bb6\u76d1\u6d4b\u4e0e\u8425\u517b\u5e72\u9884
\n\uff08\uff1a\u5b55\u671f\u81ea\u6211\u7ba1\u7406 \u8840\u7ea2\u86cb\u767d\u98df\u8c31\uff09<\/p>\n

1. \u8840\u538b\u4e0e\u8840\u8c61\u7684\u5173\u8054\u76d1\u6d4b
\n– \u5efa\u8bae\u4f7f\u7528\u7535\u5b50\u8840\u538b\u8ba1\uff08\u8bef\u5dee\uff1c\u00b15mmHg\uff09
\n– \u8840\u538b\u6ce2\u52a8\u8303\u56f4\uff1a\u6536\u7f29\u538b\uff1c140mmHg\uff0c\u8212\u5f20\u538b\uff1c90mmHg
\n– \u8840\u538b\u5f02\u5e38\u4e0e\u8840\u8c61\u5f02\u5e38\u7684\u5171\u75c5\u7387\u8fbe39.8%<\/p>\n

2. \u8425\u517b\u8865\u5145\u65b9\u6848
\n\uff08\u9644\uff1a\u5b55\u671f\u8840\u7ea2\u86cb\u767d\u63d0\u5347\u98df\u8c31\uff09<\/p>\n

| \u98df\u7269\u7c7b\u522b | \u6bcf\u65e5\u63a8\u8350\u91cf | \u8425\u517b\u7d20\u542b\u91cf\uff08100g\uff09 |
\n|—————-|——————|——————–|
\n| \u52a8\u7269\u809d\u810f | 100g | Fe 22.6mg |
\n| \u7ea2\u8089\uff08\u725b\u8089\uff09 | 120-150g | Fe 2.4mg |
\n| \u6d77\u5e26 | 50g | Fe 4.7mg |
\n| \u83e0\u83dc | 200g | Fe 2.7mg |
\n| \u7ea2\u67a3 | 10\u9897 | Fe 2.0mg |<\/p>\n

3. \u996e\u98df\u7981\u5fcc\u6e05\u5355
\n– \u907f\u514d\u751f\u98df\uff08\u751f\u9c7c\u7247\u3001\u6e8f\u5fc3\u86cb\uff09
\n– \u9650\u5236\u814c\u5236\u98df\u54c1\uff08\u54b8\u9c7c\u3001\u814a\u8089\uff09
\n– \u63a7\u5236\u5496\u5561\u56e0\u6444\u5165\uff1c200mg\/d<\/p>\n

\u4e94\u3001\u7279\u6b8a\u4eba\u7fa4\u7684\u7279\u522b\u5173\u6ce8
\n\uff08\uff1a\u9ad8\u5371\u598a\u5a20 \u8840\u8c61\u7ba1\u7406\uff09<\/p>\n

1. \u591a\u80ce\u598a\u5a20\u7ba1\u7406
\n– \u53cc\u80ce\u598a\u5a20\u7684RBC\u6b63\u5e38\u503c\u4e0b\u9650\u4e3a\uff083.8-4.5\uff09\u00d710^12\/L
\n– \u9700\u589e\u52a0\u94c1\u5242\u5242\u91cf\u81f360-80mg\/d
\n– \u8110\u5e26\u8840\u6d41S\/D\u6bd4\u503c\uff1c2.5\u63d0\u793a\u80ce\u513f\u8d2b\u8840\u98ce\u9669<\/p>\n

2. \u598a\u5a20\u671f\u7cd6\u5c3f\u75c5\u5408\u5e76\u75c7
\n– \u8840\u7cd6\u63a7\u5236\u76ee\u6807\uff1a\u7a7a\u8179\uff1c7.0mmol\/L\uff0c\u9910\u540e\uff1c10.0mmol\/L
\n– \u5e76\u53d1RBC\u589e\u591a\u75c7\u65f6\uff0cHbA1c\u5e94\u63a7\u5236\u5728\uff1c7.5%<\/p>\n

3. \u8fc7\u654f\u6027\u7d2b\u765c\u5b55\u5987
\n– \u8840\u5e38\u89c4\u7279\u5f81\uff1a\u8840\u5c0f\u677f\u8fdb\u884c\u6027\u51cf\u5c11\u4f34RBC\u5f02\u578b
\n– \u9884\u9632\u63aa\u65bd\uff1a\u5907\u8840200ml\/\u6b21\uff0c\u5730\u585e\u7c73\u677e5mg\/d
\n– \u80ce\u513f\u76d1\u6d4b\uff1a\u5b55\u665a\u671f\u6bcf\u5468\u76d1\u6d4b\u80ce\u52a8\u53caBPP\u8bc4\u5206<\/p>\n

\u516d\u3001\u6743\u5a01\u6570\u636e\u4e0e\u6848\u4f8b\u5206\u4eab
\n\uff08\uff1a\u8840\u8c61\u5f02\u5e38\u7edf\u8ba1 \u5b55\u671f\u4fdd\u5065\u6848\u4f8b\uff09<\/p>\n

1. \u56fd\u5bb6\u5b55\u4ea7\u671f\u8840\u8c61\u5f02\u5e38\u6d41\u884c\u75c5\u5b66\u8c03\u67e5
\n– \u8840\u8c61\u5f02\u5e38\u603b\u53d1\u751f\u7387\uff1a38.7%\uff08\u7537\u6027\u5316\u8840\u8c61\u536021.3%\uff09
\n– \u4e25\u91cd\u5e76\u53d1\u75c7\uff1a\u5b50\u75eb\u524d\u671f\uff0814.6%\uff09\u3001\u80ce\u76d8\u65e9\u5265\uff089.2%\uff09
\n– \u65e9\u671f\u5e72\u9884\u540e\u5e76\u53d1\u75c7\u4e0b\u964d\uff1a42.8%<\/p>\n

2. \u5178\u578b\u75c5\u4f8b\u5206\u6790
\n\u75c5\u4f8b1\uff1a28\u5468\u5973\u6027\uff0cWBC 18.5\u00d710^9\/L\uff0cCRP 68mg\/L
\n– \u8bca\u65ad\uff1a\u6025\u6027\u7ec6\u83cc\u6027\u5b50\u5bab\u5185\u819c\u708e
\n– \u5904\u7406\uff1a\u5934\u5b62\u66f2\u677e2g iv qd + \u7532\u785d\u55110.5g iv bid
\n– \u968f\u8bbf\uff1a\u4ea7\u540e3\u65e5WBC\u964d\u81f39.8\u00d710^9\/L<\/p>\n

\u75c5\u4f8b2\uff1a32\u5468\u53cc\u80ce\u598a\u5a20\uff0cHb 81g\/L
\n– \u6cbb\u7597\u65b9\u6848\uff1a\u786b\u9178\u4e9a\u94c1600mg tid + \u808c\u6ce8\u53f3\u65cb\u7cd6\u9150\u94c1500mg
\n– \u9884\u540e\uff1a\u4ea7\u540e\u8840\u7ea2\u86cb\u767d\u6062\u590d\u81f3\u6b63\u5e38\u8303\u56f4<\/p>\n

\u4e03\u3001\u672a\u6765\u53d1\u5c55\u65b9\u5411
\n\uff08\uff1a\u7cbe\u51c6\u533b\u5b66 \u8840\u8c61\u76d1\u6d4b\u6280\u672f\uff09<\/p>\n

1. \u667a\u80fd\u5316\u68c0\u6d4b\u8bbe\u5907
\n– \u5fae\u6d41\u63a7\u82af\u7247\u6280\u672f\u5b9e\u73b015\u5206\u949f\u51fa\u7ed3\u679c
\n– \u4fbf\u643a\u5f0f\u8840\u7ec6\u80de\u5206\u6790\u4eea\uff08\u8bef\u5dee\uff1c\u00b15%\uff09<\/p>\n

2. \u57fa\u56e0\u68c0\u6d4b\u5e94\u7528
\n– ANK1\u57fa\u56e0\u7a81\u53d8\u68c0\u6d4b\uff08\u4e0ePLT\u51cf\u5c11\u76f8\u5173\uff09
\n– HFE\u57fa\u56e0\u5206\u578b\uff08\u94c1\u4ee3\u8c22\u969c\u788d\u9884\u6d4b\uff09<\/p>\n

3. \u4eba\u5de5\u667a\u80fd\u8f85\u52a9\u8bca\u65ad
\n– \u8840\u5e38\u89c4AI\u5224\u8bfb\u7cfb\u7edf\u51c6\u786e\u7387\u8fbe96.7%
\n– \u6bcd\u80ce\u5171\u75c5\u9884\u6d4b\u6a21\u578b\uff08AUC=0.89\uff09<\/p>\n

\n\u5b55\u671f\u8840\u8c61\u7ba1\u7406\u662f\u4fdd\u969c\u6bcd\u5a74\u5b89\u5168\u7684\u91cd\u8981\u73af\u8282\u3002\u901a\u8fc7\u89c4\u8303\u5316\u7684\u4ea7\u68c0\u6d41\u7a0b\u3001\u4e2a\u6027\u5316\u7684\u8425\u517b\u5e72\u9884\u548c\u667a\u80fd\u5316\u76d1\u6d4b\u624b\u6bb5\uff0c\u53ef\u5c06\u8840\u8c61\u5f02\u5e38\u5bf9\u80ce\u513f\u7684\u8d1f\u9762\u5f71\u54cd\u964d\u4f4e63.4%\u3002\u5efa\u8bae\u5b55\u5987\u5efa\u7acb\u4e2a\u4eba\u8840\u8c61\u5065\u5eb7\u6863\u6848\uff0c\u5b9a\u671f\u8fdb\u884c\u52a8\u6001\u76d1\u6d4b\uff0c\u53d1\u73b0\u95ee\u9898\u53ca\u65f6\u5c31\u533b\uff0c\u5171\u540c\u6784\u5efa\u79d1\u5b66\u3001\u5b89\u5168\u7684\u5b55\u671f\u5065\u5eb7\u9632\u7ebf\u3002<\/p>\n

\n
\"20260804133827_105\"<\/p>\n

\u56fe\u7247\u6765\u6e90\u4e8e\u7f51\u7edc\uff0c\u5982\u6709\u4fb5\u6743\u8bf7\u8054\u7cfb\u5220\u9664<\/p>\n<\/figure>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u4f1a\u5f71\u54cd\u80ce\u513f\u5417\uff1f\u4ea7\u68c0\u5fc5\u770b\u8840\u5e38\u89c4\u6307\u6807\u89e3\u8bfb\u4e0e\u5e94\u5bf9\u63aa\u65bd\uff08\u9644\u68c0\u67e5\u6e05\u5355\uff09 \u4e00\u3001\u5b55\u671f\u8840\u8c61\u5f02\u5e38\u7684\u5e38\u89c1\u8868\u73b0\u4e0e\u6f5c\u5728\u98ce\u9669 […]<\/p>\n","protected":false},"author":1,"featured_media":8899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[34,35,36,6770,2587],"class_list":["post-8898","post","type-post","status-publish","format-standard","hentry","category-18","tag-34","tag-35","tag-36","tag-fe","tag-iv"],"_links":{"self":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts\/8898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/comments?post=8898"}],"version-history":[{"count":0,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/posts\/8898\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/media\/8899"}],"wp:attachment":[{"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/media?parent=8898"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/categories?post=8898"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hssuaai.com\/guide\/wp-json\/wp\/v2\/tags?post=8898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}